LIFE ALCHEMIA addresses one of the current challenges of water for human consumption such as the presence of natural radioactivity. There is a considerable lack of knowledge by the actors involved and it can be stated that, despite the current legislation (Directive 2013/51/Euratom), radioactivity is not systematically monitored at European level. Indeed, this is an environmental problem that cannot be solved at source, as it is generated by the groundwater dilution of minerals rich in radioactive isotopes, mainly from uranium (U), radium (Ra) and thorium (Th) series. Therefore, new systems able to provide sustainable removal of radioactivity from a cost-effectiveness point of view are needed. Reverse osmosis (RO) is the most commonly treatment used for this application; however carbon footprint of this process is very high and generates large volumes of water rejection with radioactivity that needs further treatment. LIFE ALCHEMIA offers a breakthrough in this problem from two angles. First, with the use of removal systems based on bed filters, which will reduce up to five times the cost of the water purification. Moreover, the whole life cycle of the radioactivity will be considered, including the management of the waste generated.